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Search for "poor"

Displaying results 1 to 3 out of 3

  Early Phase I to IIa 81%
  ... access to volunteers with symptoms, including allergic, hypertensive and hyperlipidemic subjects. Special panels of genotyped subjects such as poor metabolizers (PM) for a certain cytochrome isoenzyme are also available. CRS has access to various panels of healthy subjects, healthy ...
  Size: 32 K - Created: 18-11-12 - Modified: 07-10-19 14:37
Path: /Services/Early Phase I to IIa

  Special Populations 79%
  ... is part of CRS’s standard routine. Genotyped Subjects: Over 3,000 healthy subjects are genotyped for the cytochrome P450 genes CYP2D6 (> 100 poor metabolizers), CYP2C9 (> 170 PM) and CYP2C19 (> 90 PM). Additional panels such as UGT1A1 characterisation are in preparation. Special Patient ...
  Size: 32 K - Created: 18-11-12 - Modified: 02-08-19 10:27
Path: /Expertise/Special Populations

  2010-2020 54%
  ... O, Gundorf Drewes P, Rembratt A, Schultz A, Timmer W, (2012) Pharmacokinetic and tolerability profile of pridopidine in healthy-volunteer poor and extensive CYP2D6 metabolizers, following single and multiple dosing. Eur J Drug Metab Pharmacokinet 2012, Sept 5 (Epub ahead of print) ...
  Size: 72 K - Created: 09-11-15 - Modified: 14-10-20 09:56
Path: /Expertise/Published Expertise/2010-2020